Dr. Hassan Mahmoud Ghonaim

Design and optimization of advanced oral and parenteral drug delivery systems, with a focus on solid dosage forms, self‑nanoemulsifying systems (SNEDDS), and modified‑release technologies.​

Development of nanostructured lipid carriers and solid lipid nanoparticles for targeted and controlled delivery of anticancer and anti‑inflammatory drugs.​

Non‑viral gene and siRNA delivery using rationally designed lipopolyamines and lipid–aminoglycoside conjugates, including structure–activity relationship studies and safety optimization.​

Transdermal and dermal delivery, model skin membranes, and the impact of natural oils and excipients on skin barrier function and permeability.​

Biopharmaceutics and pharmacokinetics of brand and generic products, including in‑vitro / in‑vivo correlation, dissolution profiling, and quality equivalence of multisource medicines.​

Formulation–performance relationships in tablet and capsule technologies, including excipient selection, solubility enhancement, and improvement of dissolution and bioavailability of BCS class II drugs.​